Endocrine Abstracts

Hypothyroidism due to autoimmune aetiology can be associated with other autoimmune conditions such as Type 1 Diabetes Mellitus (T1DM) and primary adrenal insufficiency. Ruling out primary adrenal insufficiency is important in any patient with suspected autoimmune hypothyroidism.Case: 43-year-old female complaining of general lethargy, sore throat, and neck pain. She was found to be hyponatraemic (Na+ 130) after being reviewed by the GP and was advised to...

Introduction: Background: Pituitary adenomas can be divided into functioning pituitary adenoma (FPA) and non-functioning pituitary adenoma (NFPA). Pituitary adenomas can also be classified based on their size as microadenoma(<1cm) or macroadenoma (>1cm).Cases: 1. A 33-year male was admitted with a 4-month history of headaches, generalized aches and pains, weight loss, lethargy, and erectile dysfunction. He was reviewed by t...

Introduction: Multiple Endocrine Neoplasms (MEN) are a group of rare hereditary tumours which have strong predisposition to endocrine organs. MEN1 is an autosomal-dominant inherited neoplasm with a broad genetic phenotype, characterised by synchronised or asynchronous triad neoplasms localised in the anterior pituitary, parathyroid and pancreas (Kamilaris and Stratakis, 2019; Li et al., 2022). Despite advances in the fields of diagnostic techniques and therapies, MEN1...

Introduction: Amiodarone is a highly effective drug, used for the treatment of arrhythmias. However, it can cause either hypothyroidism or thyrotoxicosis. It leads to alterations in thyroid gland function or thyroid hormone metabolism, due to its high iodine content. Amiodarone-induced hypothyroidism is common in countries with high iodine dietary intake, and Amiodarone-induced thyrotoxicosis is more prevalent in regions with low iodine dietary intake. A large amount of iodide...